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Ȩ Ȩ > ¿¬±¸¹®Çå > ±¹³» ³í¹®Áö > Çѱ¹Á¤º¸Åë½ÅÇÐȸ ³í¹®Áö (Journal of the Korea Institute of Information and Communication Engineering)

Çѱ¹Á¤º¸Åë½ÅÇÐȸ ³í¹®Áö (Journal of the Korea Institute of Information and Communication Engineering)

Current Result Document :

ÇѱÛÁ¦¸ñ(Korean Title) °øÃÊÁ¡ ´ÜÃþ À̹ÌÁö¿¡¼­ ¼öÁغ° ÀâÀ½Á¦°Å¿Í Ŭ·¯½ºÅÍ °æ°è¼± ÃßÃâ
¿µ¹®Á¦¸ñ(English Title) Graded Noise Elimination and Cluster Boundary Extraction in Confocal Sliced Images
ÀúÀÚ(Author) Á¶¹Ì°æ   ±èÁø¼®   ½ÉÀç¼ú   Migyung Cho   Jinseok Kim   Jaesool Shim  
¿ø¹®¼ö·Ïó(Citation) VOL 15 NO. 12 PP. 2697 ~ 2704 (2011. 12)
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(Korean Abstract)
Á¶Á÷ °øÇп¡¼­´Â ÇÏÀ̵å·Î Á© ³» 3Â÷¿ø ¼¼Æ÷ ¹è¾ç °úÁ¤¿¡¼­ ¼¼Æ÷¿Í ¼¼Æ÷°£ÀÇ °ø»ý°ü°è¸¦ °üÂûÇÏ°Ô µÇ´Âµ¥, ½Ã°£ÀÌ °æ°úÇÔ¿¡ µû¶ó ¼¼Æ÷µéÀÇ Áõ°¡³ª »óÈ£ÀÛ¿ë, ºÐÈ­, »ç¸êµÇ´Â °úÁ¤µéÀ» °í¹èÀ² °øÃÊÁ¡ Çö¹Ì°æÀ» ÀÌ¿ëÇÏ¿© ´ÜÃþ ÃÔ¿µÇÏ°í, ÃÔ¿µµÈ À̹ÌÁöµé·ÎºÎÅÍ ¼¼Æ÷ÀÇ °ø»ý ¸ÞÄ¿´ÏÁòÀ̳ª º¯È­ °úÁ¤À» °üÂû ¹× ºÐ¼®Çϱâ À§ÇÑ ¿¬±¸°¡ ÁøÇàµÇ°í ÀÖ´Ù. º» ¿¬±¸¿¡¼­´Â ÇÏÀ̵å·Î Á© ³» 3Â÷¿ø ¼¼Æ÷ ¹è¾ç °úÁ¤¿¡¼­ ´ÜÃþ ÃÔ¿µµÈ ¼¼Æ÷ À̹ÌÁö·ÎºÎÅÍ Å¬·¯½ºÅÍ °æ°è¼± Á¤º¸¸¦ ÃßÃâÇϱâ À§ÇÑ ¼öÁغ° ÀâÀ½ Á¦°Å ¹æ¹ý°ú Ŭ·¯½ºÅÍ °æ°è¼± ÃßÃâ ¹æ¹ýÀ» Á¦¾ÈÇÏ¿´´Ù. ½ÇÇèÀ» ÅëÇØ Á¦¾ÈµÈ ¹æ¹ýÀº ÇÏÀ̵å·ÎÁ©·Î ÀÎÇÑ Á¼½Ò ¸ð¾çÀÇ ÀâÀ½¿¡ ¶Ù¾î³­ ÀâÀ½ Á¦°Å ¼º´ÉÀ» º¸¿© ÁÙ »Ó¸¸ ¾Æ´Ï¶ó º¹ÀâÇÑ Å¬·¯½ºÅ͵鿡 ´ëÇؼ­µµ Á¤È®ÇÑ Å¬·¯½ºÅÍ °æ°è¼±À» ÃßÃâÇÔÀ» º¸¿© ÁÖ¾ú´Ù.
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(English Abstract)
In tissue engineering area, many researchers observe symbiotic relationship such as proliferation, interaction, division apoptosis with time between cells in process of the 3D cell culture in hydrogels. The 3D cell culture process can be taken photographs into sliced images using confocal microscope. Symbiotic mechanism and changes of cell behaviors can be observed and analyzed from the images acquired by confocal microscope. In this paper, we proposed and developed graded noise elimination method and cluster boundary extraction method to extract boundaries information from sliced confocal images acquired in process of the 3D cell culture in hydrogels. The experiment based algorithm showed excellent performance for eliminating noises that have very small millet-shaped size. It is also showed to extract exact boundaries information for even complex clusters.
Å°¿öµå(Keyword) °øÃÊÁ¡ À̹ÌÁö   ¼¼Æ÷ À̹ÌÁö ºÐ¼®   ÀâÀ½ Á¦°Å   °æ°è¼± ÃßÃâ   ¹ÙÀÌ¿À ³ª³ë   Confocal Image   Analysis of cell image   Noise elimination   Boundary extraction   Bio-nano  
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