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Ȩ Ȩ > ¿¬±¸¹®Çå > ±¹³» ³í¹®Áö > Çѱ¹Á¤º¸°úÇÐȸ ³í¹®Áö > Á¤º¸°úÇÐȸ³í¹®Áö (Journal of KIISE)

Á¤º¸°úÇÐȸ³í¹®Áö (Journal of KIISE)

Current Result Document : 100 / 589 ÀÌÀü°Ç ÀÌÀü°Ç   ´ÙÀ½°Ç ´ÙÀ½°Ç

ÇѱÛÁ¦¸ñ(Korean Title) À¥ ±â¹Ý ÃÊ°í¼Ó ½Å¾à Èĺ¸¹°Áú Ž»ö-°è»ê ½Ã½ºÅÛ ±¸Çö
¿µ¹®Á¦¸ñ(English Title) Implementation of Web-based High-Throughput Screening Calculation System
ÀúÀÚ(Author) Á¶¼ºÈ£   ±èÀÎÈñ   °øÁö¿ø   ±è´ë»ê   ±Ç³²ÈÆ   ·Î¹öÆ® E. º£¸®¾î   ±è¼ºÈÆ   Seong-ho Cho   Inhee Kim   Jiwon Kong   Daesan Kim   Namhoon Kwon   Robert E. Burrier   Sunghoon Kim  
¿ø¹®¼ö·Ïó(Citation) VOL 46 NO. 03 PP. 0260 ~ 0267 (2019. 03)
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(Korean Abstract)
ÀÌ ³í¹®¿¡¼­´Â nanoluciferase ½Ã½ºÅÛÀÇ »ýÈ­ÇÐ ¹ÝÀÀ °úÁ¤¿¡¼­ µµÃâÇÑ µ¥ÀÌÅ͸¦ °í¼ÓÀ¸·Î °è»êÇÏ°í ½Å¾à Èĺ¸¹°ÁúÀ» ½Å¼ÓÈ÷ ã¾Æ³»µµ·Ï º¸Á¶ÇÏ´Â À¥ ±â¹Ý ÃÊ°í¼Ó °è»ê-Ž»ö ½Ã½ºÅÛ(HTSCS) °³¹ß °á°ú¹°À» ¼³¸íÇÑ´Ù. ÀÌ ½Ã½ºÅÛ¿¡¼­´Â ´ÜÀÏ ³óµµ(Single-Dose)¿Í ´ÙÁß ³óµµ(Multi-Dose)·Î ¼¼Æ÷ ½ÇÇèü¿¡ Èĺ¸ ¹°ÁúÀ» Åõ¿©(in-vitro)ÇÑ ´ë·®ÀÇ ½ÇÇè µ¥ÀÌÅ͸¦ °è»êÇÏ¿©, Â÷Æ® ¹× ±×·¡ÇÁ Á¤º¸·Î ³ªÅ¸³½´Ù. µû¶ó¼­ HTSCS ½Ã½ºÅÛÀ¸·Î ½Å¾à Èĺ¸¹°Áú ¹ß°ß¿¡ ÇÊ¿äÇÑ ½Ã°£°ú ³ë·ÂÀ» ÁÙÀÏ ¼ö ÀÖ´Ù.
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(English Abstract)
In this paper, we describe the development of a web-based HTSCS (High Throughput Screening Calculation System), which is the process for assisting high-speed screening and calculation of drug candidates based on biochemical reactions from Nanoluciferase system. This system calculates and displays large amounts of experimental data with single-dose and multi-dose concentration in-vitro cell experiments through charts and graphs. Therefore, we can utilize the HTSCS to save time and effort required for drug screening.
Å°¿öµå(Keyword) °í¼Ó ½Å¾à Ž»ö   ¹ß±¤ ÀÎÀÚ ½ÇÇè   ½Å·Ú ±¸°£ ¹Ý¿µ ¾Ë°í¸®Áò   ºñ¼±Çü ȸ±Í ºÐ¼®   µ¥ÀÌÅÍ Á¤ÇüÈ­   high-throughput screening   luciferase assay   trust region reflective algorithm   nonlinear regression analysis   data structuration  
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