Çѱ¹Á¤º¸Åë½ÅÇÐȸ ³í¹®Áö (Journal of the Korea Institute of Information and Communication Engineering)
Current Result Document : 3 / 3
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ÇѱÛÁ¦¸ñ(Korean Title) |
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¿µ¹®Á¦¸ñ(English Title) |
Efficacy of Gene Transfer and Expression of Novel Recombinant Baculovirus Vector |
ÀúÀÚ(Author) |
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Tae-Dong Kweon
Seong-Karp Hong
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¿ø¹®¼ö·Ïó(Citation) |
VOL 18 NO. 08 PP. 2017 ~ 2022 (2014. 08) |
Çѱ۳»¿ë (Korean Abstract) |
Æú¸®È÷µå·Ð ÇÁ·Î¸ðÅÍ, ¼öÆ÷¼º±¸³»¿° ¹ÙÀÌ·¯½ºG, Æú¸®A, »çÀÌÅä¸Þ°¡¹ÙÀÌ·¯½º ÇÁ·Î¸ðÅÍ, °È³ì»öÇü±¤´Ü¹éÁú, ´Ü¹éÁúÀü´ÞºÎÀ§ À¯ÀüÀÚ µîÀ» Æ÷ÇÔÇÑ »õ·Î¿î º£Å§·Î¹ÙÀÌ·¯½º ½Ã½ºÅÛÀÌ Á¦Á¶µÇ¾ú´Ù. º» ÀçÁ¶ÇÕº¤ÅÍ ½Ã½ºÅÛÀº Àΰ£ ¼¶À¯¾Æ¼¼Æ÷¿¡ Àû¿ëÇÏ¿© ½ÃÇèÇÏ¿´°í ÀçÁ¶ÇÕµÈ À¯ÀüÀÚÀÇ Àü´Þ°ú À¯ÀüÀÚ ¹ßÇöÀ» ´ëÁ¶ º¤ÅͽýºÅÛ°ú ºñ±³ÇÏ¿´´Ù. º» ¿¬±¸·ÎºÎÅÍ »õ·Ó°Ô Á¦ÀÛµÈ º» º£Å§·Î¹ÙÀÌ·¯½º ½Ã½ºÅÛÀÌ À¯ÀüÀÚÀÇ ÀüÀÌ¿Í À¯ÀüÀÚ ¹ßÇö ¸é¿¡¼ ´ëÁ¶ º¤ÅͽýºÅÛ º¸´Ù °íÈ¿À²À» ³ªÅ¸³»¾ú´Ù.
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¿µ¹®³»¿ë (English Abstract) |
Novel baculovirus vector systems recombined with coding genes of polyhedron promoter, vesicular stomatitis virus G (VSVG), polyA, cytomegalovirus (CMV) promoter, enhanced green fluorescent protein (EGFP), and protein transduction domain (PTD) were constructed. These recombinant baculovirus vector systems were applied into human foreskin fibroblast cells and compared the effects of gene transfer and gene expression of these recombinant baculovirus vector systems with control vector system. From this study, it showed that these novel recombinant baculovirus vector systems were superior efficacy to control vector system in view of gene transfer and gene expression.
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Å°¿öµå(Keyword) |
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°È³ì»öÇü±¤´Ü¹éÁú
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¼öÆ÷¼º±¸³»¿° ¹ÙÀÌ·¯½ºG
baculovirus
enhanced green fluorescent protein
protein transduction domain
vesicular stomatitis virus G
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