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Current Result Document :
ÇѱÛÁ¦¸ñ(Korean Title) |
´Ü¹éÁú 2-DE À̹ÌÁö ºÐ¼®¿¡¼ Á¤È®ÇÑ ½ºÆÌ ¸ÅĪ ÆÐÅÏ °Ë»öÀ» À§ÇÑ È¿°úÀûÀÎ ¹æ¹ý |
¿µ¹®Á¦¸ñ(English Title) |
An Efficient Method to Find Accurate Spot-matching Patterns in Protein 2-DE Image Analysis |
ÀúÀÚ(Author) |
±è¿¬È
ÀÌ¿ø¼®
Yanhua Jin
Won Suk Lee
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¿ø¹®¼ö·Ïó(Citation) |
VOL 16 NO. 05 PP. 0551 ~ 0555 (2010. 05) |
Çѱ۳»¿ë (Korean Abstract) |
´Ü¹éÁú 2-DE À̹ÌÁö ºÐ¼®¿¡¼ ´Ü¹éÁú ÀÚü°¡ °¡Áö°í ÀÖ´Â ºÒ¾ÈÁ¤¼º°ú 2-DE ½ÇÇèÀÌ °¡Áö°í ÀÖ´Â ±Ùº»ÀûÀÎ ¹®Á¦Á¡À¸·Î ÀÎÇÏ¿© À̹ÌÁö ½ºÆÌ ¸ÅĪ ºÐ¼®ÀÇ Á¤È®µµ°¡ ³·¾ÆÁö°Ô µÈ´Ù. ÀÌ ³í¹®¿¡¼´Â ´ÙÁß ÂüÁ¶À̹ÌÁö¸¦ »ç¿ëÇÏ¿©, ½ºÆÌ ¸ÅĪ ÆÐÅÏÀÇ Á¤È®µµ¿¡ Å« ¿µÇâÀ» ÁÖ´Â À̹ÌÁö Âî±×·¯ÁüÀ» º¸¿ÏÇÏ°í, ±×¿¡ µû¸¥ ³ëÀÌÁî ½ºÆÌ Á¦°Å¿Í ÂüÁ¶ À̹ÌÁö Ç°Áú¿¡ ÀÇÇÑ Á¤È®µµ ÀúÇϸ¦ ÃÖ¼ÒÈÇÏ´Â ¹æ¹ýÀ» Á¦¾ÈÇÏ¿´´Ù. ¶ÇÇÑ 2-DE À̹ÌÁöÀÇ µ¥ÀÌÅÍ Æ¯¼º¿¡ ÀÇÇÏ¿© À̹ÌÁö ¼ö°¡ Áõ°¡ÇÒ ¶§ ¼º´ÉÀÌ ±Þ°ÝÈ÷ ¶³¾îÁö´Â ¹®Á¦¸¦ ÇØ°áÇϱâ À§ÇÏ¿©, ´ÙÁß ÂüÁ¶À̹ÌÁö¸¦ »ç¿ëÇÏ¿© ±¸ÃàÇÑ ½ºÆÌ ¸ÅĪ µ¥ÀÌÅͺ£À̽º¸¦ À̹ÌÁöÀÇ »ý¹°ÇÐÀû Ư¼º¿¡ ÀÇÇÏ¿© ¡°ºÐÇÒ ¹× È®À塱 ¹æ¹ýÀ» »ç¿ëÇÏ¿©, Á¤È®µµ¸¦ Çâ»ó½ÃÅ°´Â µ¿½Ã¿¡ ÆÐÅÏ ±æÀ̸¦ º¸ÀåÇÏ´Â ½ºÆÌ ¸ÅĪ ÆÐÅÏÀ» È¿°úÀûÀ¸·Î »ý¼ºÇÏ¿´´Ù. ½ÇÇè¿¡¼´Â ½ÇÁ¦ Àΰ£ 2-DE À̹ÌÁö µ¥ÀÌÅ͸¦ »ç¿ëÇÏ¿© Á¦¾ÈÇÑ ¹æ¹ýÀÇ Å¸´ç¼ºÀ» º¸¿©ÁØ´Ù. |
¿µ¹®³»¿ë (English Abstract) |
In protein 2-DE image analysis, the accuracy of spot-matching operation which identifies the spot of the same protein in each 2-DE gel image is intensively influenced by the errors caused by the various experimental conditions. This paper proposes an efficient method to find more accurate spot-matching patterns based on multiple reference gel images in spot-matching pattern analysis in protein 2-DE image analysis. Additionally, in order to improve the reduce the execution time which is increased exponentially along with the increasing number of gel images, a ¡°partition then extension¡± framework is used to find spot-matching pattern of long length and of higher accuracy. In the experiments on real 2-DE images of human liver tissue are used to confirm the accuracy and the efficiency of the proposed algorithm. |
Å°¿öµå(Keyword) |
2-DE À̹ÌÁö
½ºÆÌ ¸ÅĪ
À̹ÌÁö ºÐ¼®
ÆÄƼ¼Ç
ºó¹ß ÆÐÅÏ
2-DE image
spot-matching
image analysis
partition
frequent pattern
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ÆÄÀÏ÷ºÎ |
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