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Ȩ Ȩ > ¿¬±¸¹®Çå > ±¹³» ³í¹®Áö > Çѱ¹Á¤º¸Ã³¸®ÇÐȸ ³í¹®Áö > Á¤º¸Ã³¸®ÇÐȸ ³í¹®Áö B

Á¤º¸Ã³¸®ÇÐȸ ³í¹®Áö B

Current Result Document : 4 / 5

ÇѱÛÁ¦¸ñ(Korean Title) ÅäÆú·ÎÁö¸¦ ¹Ý¿µÇÑ ´Ü¹éÁú ¹ÝÁ¡ ÀÚµ¿ Á¤ÇÕ
¿µ¹®Á¦¸ñ(English Title) Automatic Matching of Protein Spots by Reflecting Their Topology
ÀúÀÚ(Author) Ankhbayar Yukhuu   ÀÌÁ¤¹è   Ȳ¿µ¼·   Ankhbayar Yukhuu   Jeong-Bae Lee   Young-Sup Hwang  
¿ø¹®¼ö·Ïó(Citation) VOL 17-B NO. 01 PP. 0079 ~ 0084 (2010. 02)
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(Korean Abstract)
µÎ °³ÀÇ ÀÌÂ÷¿ø ´Ü¹éÁú Àü±â¿µµ¿ ¿µ»ó¿¡¼­ ÇÑÂÊ ¿µ»óÀÇ °¢ ¹ÝÁ¡ÀÌ ´Ù¸¥ ¿µ»óÀÇ ¾î´À ¹ÝÁ¡°ú ÀÏÄ¡ÇÏ´Â Áö ¾Ë¾Æ³»´Â ÀÏÀº ´Ü¹éÁúÀÇ »ý¼º°ú ¼Ò¸ê, º¯ÀÌ µîÀ» ¾Ë ¼ö ÀÖ°Ô ÇÏ´Â Áß¿äÇÑ ÀÏÀÌ´Ù. ´Ü¹éÁú ¹ÝÁ¡Àº ÁÖ·Î 2Â÷¿ø Àü±â¿µµ¿¿¡ ÀÇÇØ ºÐ¸®µÈ´Ù. ÀÌ °úÁ¤Àº Á¶Á÷ÀÇ »óÅÂ, ½ÇÇè Á¶°Ç µî¿¡ µû¶ó °°Àº ´Ü¹éÁúÀÌ¶óµµ ±× À§Ä¡°¡ Á¶±Ý¾¿ ´Ù¸£°Ô µÈ´Ù. °¢ ¹ÝÁ¡À» Á¤ÇÕÇÏ¿© º¸¸é ±ÕÀÏÇÏÁö ¾ÊÀº ºñ¼±Çü º¯È¯ °ü°è¸¦ ÀÌ·é´Ù. ±×·¯³ª ±¹ÁöÀûÀ¸·Î º¸¸é ¹ÝÁ¡ »çÀÌÀÇ ÅäÆú·ÎÁö°¡ À¯ÁöµÇ´Â °ÍÀ» º¼ ¼ö ÀÖ´Ù. º» ¿¬±¸´Â ÀÌ·¯ÇÑ ÅäÆú·ÎÁöÀÇ À¯Áö¿¡ Âø¾ÈÇÏ¿© ¹ÝÁ¡³¢¸® Á¤ÇÕÇÏ´Â ¹æ¹ýÀ» Á¦¾ÈÇÑ´Ù. ÅäÆú·ÎÁöÀÇ À¯»ç¼ºÀ» ºñ±³Çϱâ À§ÇÏ¿© ÀÌ¿ôÇÑ ¹ÝÁ¡°úÀÇ °Å¸®¿Í °¢µµ¸¦ ºñ±³ÇÏ¿´´Ù. ½ÇÇèÀ» ÅëÇÏ¿© Á¦¾ÈÇÑ ¹æ¹ýÀÌ ¿ì¼öÇÔÀ» º¸¿´´Ù.
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(English Abstract)
Matching spots between two sets of 2-dimensional electrophoresis can make it possible to find out the generation, extinction and change of proteins. Generally protein spots are separated by 2-dimensional electrophoresis. This process makes the position of the same protein spot a little different according to the status of the tissue or the experimental environment. Matching the spots shows that the relation of spots is non-uniform and non-linear transformation. However we can also find that the local relation preserves the topology. This study proposes a matching method motivated by the preservation of the topology. To compare the similarity of the topology, we compared the distance and the angle between neighbour spots. Experimental result shows that the proposed method is effective.
Å°¿öµå(Keyword) ¹ÝÁ¡ Á¤ÇÕ   ´Ü¹éÁú   ÅäÆú·ÎÁö   Àü±â¿µµ¿   Spot Matching   Protein   Topology   Electrophoresis  
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