Á¤º¸Ã³¸®ÇÐȸ ³í¹®Áö ÄÄÇ»ÅÍ ¹× Åë½Å½Ã½ºÅÛ
Current Result Document :
ÇѱÛÁ¦¸ñ(Korean Title) |
´Ü¹éÁú ºÐÀÚ¿¡¼ º¯ÇüµÈ ä³Î ¹ß°ßÀ» À§ÇÑ À¯È¿ »çÀ̵å üÀÎ ¹èÄ¡ ¾Ë°í¸®Áò |
¿µ¹®Á¦¸ñ(English Title) |
An Algorithm for Computing Valid Side Chain Conformations for Finding Transformed Channels in a Protein Molecule |
ÀúÀÚ(Author) |
ÃÖÁöÈÆ
±èº´ÁÖ
±è±¸Áø
Jihoon Choi
Byungjoo Kim
Ku-Jin Kim
|
¿ø¹®¼ö·Ïó(Citation) |
VOL 04 NO. 01 PP. 0001 ~ 0004 (2015. 01) |
Çѱ۳»¿ë (Korean Abstract) |
º» ³í¹®¿¡¼´Â ÁÖ¾îÁø ä³ÎÀÌ º¯ÇüµÉ ¶§, ¾Æ¹Ì³ë»êµéÀÇ À¯È¿ÇÑ »çÀ̵å üÀÎ ¹èÄ¡(side chain conformation)¸¦ ã´Â ¾Ë°í¸®ÁòÀ» Á¦½ÃÇÑ´Ù. Á¦¾ÈµÈ ¾Ë°í¸®ÁòÀº ¾Æ¹Ì³ë»êÀÇ À¯¿¬¼º¿¡ ±Ù°ÅÇÏ¿© »çÀ̵å üÀÎ À¯¿¬¼ºÀ» °¡Áø ´Ü¹éÁú ºÐÀÚ¸¦ ±¸ÇöÇÏ°í, ä³Î º¯È¿¡ ¿µÇâÀ» ÁÖ´Â ÀÎÁ¢ ¾Æ¹Ì³ë»ê(adjacent amino acid)À» ÃßÃâÇÑ´Ù. ÀÎÁ¢ ¾Æ¹Ì³ë»ê°ú ÀÌ¿ô(neighbor) ¾Æ¹Ì³ë»êÀÇ Ãæµ¹ °Ë»ç¸¦ ¼öÇàÇÏ¿© À¯È¿ÇÏÁö ¾ÊÀº »çÀ̵å üÀÎ ¹èÄ¡¸¦ Á¦°ÅÇÑ ÈÄ, ȸÀü°¢ Á¶ÇÕ Æ®¸®(rotation angle combination Tree)¸¦ ±¸¼ºÇÏ¿© »çÀ̵å üÀÎ ¹èÄ¡ Áß À¯È¿ÇÑ °Íµé¸¸À» ÃßÃâÇÑ´Ù.
|
¿µ¹®³»¿ë (English Abstract) |
This paper presents an algorithm for finding valid side chain conformations of amino acids, when given channel is transformed. Thesuggested algorithm implements a protein molecule with flexible side chains based on the flexibility of amino acids, and extracts adjacent amino acids that affect the formation of the channel. We detect the collision between adjacent amino acids and neighbors, in order to exclude invalid side chain conformations. Then, we construct the rotation angle combination tree to choose valid side chain conformations.
|
Å°¿öµå(Keyword) |
À¯¿¬¼ºÀ» °¡Áø ´Ü¹éÁú ºÐÀÚ
»çÀ̵å üÀÎ ¹èÄ¡
Rotamer Angle
ä³Î
|
ÆÄÀÏ÷ºÎ |
PDF ´Ù¿î·Îµå
|